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Ghaedi, Pharmacol
A recent post hoc analysis of the CREDENCE (canagliflozin and renal events in diabetes with established nephropathy clinical evaluation) and DAPA-CKD (dapagliflozin and prevention of adverse outcomes in chronic kidney disease) trials found that SGLT-2 inhibitor use was associated with a lower rate of discontinuation of renin-angiotensin-aldosterone system inhibitors compared with placebo during follow-up in patients with albuminuric chronic kidney disease
Fold change in DiI-labelled LDL (c) and HDL (d) uptake of A-498 cells upon treatment with heparinases (0.1 U/mL), chondroitinase (0.1 U/mL), or both (blue), relative to uptake of untreated cells
