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In a landscape where biopharmaceutical innovation is rapidly expanding, particularly in the field of peptide and protein therapeutics, the ability to develop reliable analytical methods remains essential

Shelf Life Summary Powder (fridge): 1224 months Powder (freezer): 24+ years Reconstituted liquid (fridge): 38 weeks Reconstituted liquid (frozen aliquots): Several months with cryoprotectant Dont Do This Dont use tap or boiled water

The compound occurs naturally in the human body - intracorporeal production of L-carnitine occurs in the liver and kidneys, and the substance accumulates mainly in the heart muscle and skeletal muscles

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The bio-availability of the DPP-4 inhibitors is very good and the pharmacodynamic- as well as the pharmacokinetic characteristics lead to the above mentioned clinically sufficient DPP-4 inhibition with once daily dosing (only vildagliptin has to be dosed twice daily) (18, 19)