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Animal models point to a signal of decreased vascular oxidative stress and inflammation as the driving mechanism of that benefit (187, 200, 201)

Oxidized Glutathione (Japan, 10 weeks, 2%): Reduced melanin, improved smoothness, and increased moisture

GLP-1RAs alleviate vascular aging under chronic stress via increasing adiponectin (APN) levels and inhibiting aortic MMP-9 and MMP-2 expression in ApoE -/- mice [96, 149]

Lpez-Cano C, Santos MD, Snchez E, et al