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For most people on GLP-1s, yes - especially early on

Final Thoughts: A Promising Tool, But Not a One-Size-Fits-All Solution GLP-1 medications are a powerful option for addressing metabolic challenges that can affect fertility, especially in patients with PCOS or obesity

Ridker PM, Bhatt DL, Pradhan AD, Glynn RJ, MacFadyen JG, Nissen SE (2023) Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy: a collaborative analysis of three randomised trials

However, it remains unclear whether this reduction is due to decreased release from the pineal gland, increased breakdown of the hormone, or a combination of both factors