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Post-surgery, these individuals may still be clinically overweight or obese even after treatment as shown in a 6-year follow up trial of sleeve gastrectomy patients, mean BMI was 39 (obese class II) but micronutrient deficiencies were extensive

The FDA labeling recommends using non-oral contraceptive methods or adding a barrier method (condoms, diaphragm) for four weeks after starting tirzepatide and for four weeks after each dose escalation