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Although some of these people may have had a lower suicide risk to begin with, even before they started taking semaglutide, the results from the study are still reassuring.' Results show drug could be used beyond diabetes The comprehensive analysis, published in the journal eClinicalMedicine, used more than 100 million patient records in the USA including over 20,000 who were taking semaglutide
It works by mimicking the action of endogenous GLP-1, a hormone that stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and promotes satiety through central nervous system pathways
The study subjects were all undergoing standard treatment with metformin, sulfonylureas, or both