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It can also be more cost-effective

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In the SURMOUNT-1 trial, participants on 10mg achieved an average weight reduction of 21.4%, losing roughly 49 pounds over 72 weeks

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weight loss by people not meeting guidelines), and safety/ethical issues, especially in direct-to-consumer contexts

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But how replicable is that data

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Tirzepatide targets two hormone pathways, while Retatrutide is studied for triple-pathway signaling

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