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Lower doses still produced meaningful results, but the greatest reductions were seen at the upper end of the dosing range

Noncanonical sites of adult neurogenesis in the mammalian brain

The antidiabetic drug liraglutide minimizes the non-cholinergic neurotoxicity of the pesticide mipafox in SH-SY5Y cells

Gupta, S

The underlying molecular mechanism allowing this dysmetabolic dependent effect involves P4HA1 function, an enzyme deputed to collagen biosynthesis and fibril formation [23, 63], in the stromal compartment, putting it under the spotlight as a potential early PDAC biomarker particularly sensitive to metabolic alterations