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This suppressed glucose uptake, glycolytic enzymes, mitochondrial biogenesis, and electron transport chains, exacerbating mitochondrial damage
Drug therapy for idiopathic male infertility: rationale versus evidence
INS-1 cells were cultured in RPMI-1640 medium containing 11.1 mM glucose supplemented with 10% fetal bovine serum (FBS), 100 U/ml penicillin, 100 g/ml streptomycin, 10 mM HEPES, 2 mM L-Glutamine, 1 mM sodium pyruvate, and 50 M -mercaptoethanol
Older adults often have multiple health conditions, take several medications, and experience age-related physiological changes that can influence drug safety and tolerability
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