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In contrast, SIRT3 and SIRT5 improve mitochondrial function, as manifested by reduced ROS production during oxidative phosphorylation (136)

No clinical studies have evaluated antioxidant efficacy in biomarker-defined ASD groups, and standardized criteria for identifying such profiles remain lacking

D.Hernandez-VelascoX.et al (2016)

Patients experiencing persistent vomiting or diarrhea should be monitored for signs of dehydration and renal dysfunction, with appropriate fluid replacement and potentially temporary discontinuation of the medication if necessary

A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer