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PMID: 30089501

This coordination stabilizes copper in a biologically available form, allowing it to interact with cellular targets without generating oxidative stress. The copper ion also acts as a catalytic cofactor in enzymes involved in collagen cross-linking, antioxidant defense, and wound remodeling

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Acknowledgements The authors would like to thank every researcher that contributed to the understanding of the close relationship between the IGF-1 deficiency and the Metabolic Syndrome establishment

References Cited Ahmet U, Abdurrahman K, Sait B, Ahmet E, Salih D, Mendane S, Ates Y, Fatih B, Necmettin K, Kemal D