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2004) have shown to decrease AUC of mycophenolic acid (immunosuppressive) when patient had either or both polymorphisms (Kuypers et al., 2005) Non-carriers of the T-275A and C-2152T 1A9 promoter polymorphisms (low 1A9 expressors) showed a trend toward increased gastrointestinal toxicity of mycophenolic acid

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Refrigerate Immediately: The reconstituted vial must be stored in a refrigerator, typically between 2C and 8C (36F and 46F)

Accessed June 25, 2024.

The logic behind this policy relates to the tirzepatide titration schedule