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Options for managing tolerance include a brief dose reduction for 4 to 8 weeks ("drug holiday" at a lower dose, not complete cessation), lifestyle optimization to maximize the medication effect, evaluation for other contributing factors (thyroid function, cortisol, sleep quality, medication interactions), and consideration of adding a complementary compound to address specific aspects of the plateau
HRT has also been shown to help reduce belly fat brought on by the hormonal changes that happen during menopause
Subcutaneous injection represents the most practical administration route for self-injection
The comedogenic rating of 4 comes from the 1972 rabbit ear model using undiluted ingredients
Independently verified Tested by an accredited US third-party lab for identity, purity, and concentration
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