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Common Adverse Effects of GLP-1-Based Therapies Gastrointestinal (GI) Side Effects Gastrointestinal discomfort is the most frequently reported side effect of GLP-1-based therapies, including single, dual, and triple agonists

A useful detail: the studies included two real-world groups: 1) People who were using positive airway pressure (PAP) therapy (like CPAP) 2) People who were unable or unwilling to use PAP That matters because in real life, a lot of people struggle with PAP adherence

Among children the gap is even wider

Both treatments also reduced broader secondary endpoints, including urgent visits and additional HF-related events, with no significant safety concerns identified

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