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Plasma DPP-4 activity, glucose tolerance, body weight, plasma active GLP-1, and TG levels were not different in RC-fed Dpp4 Gut/ mice, whether examined in the fasting state or following olive oil gavage (Figure 2, G and H, and Supplemental Figure 1, G and H)

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After 4 h at 37 C, transfection mix was removed and medium containing 0.1% FBS and 1% PenStrep and compounds (Aloxistatin, S7393, Selleckchem

(13) These findings suggest a promising osteogenic role for GLP-1 therapies, especially in metabolic disease contexts