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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
However, this was just a pilot study with a small group of participants, so much more work is needed
I grew up in Lafayette, went to high school at a small Well, big for Lafayette, at the Catholic school system in a Catholic high school
These effects are typically dose-dependent and may diminish over time
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