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Semaglutide delays gastric emptying, which could potentially interfere with the fasting and eating windows of intermittent fasting [11]
Health Canada added that it is currently reviewing eight other submissions for generic semaglutide by different companies and expects to make additional regulatory decisions in the coming weeks and months. The regulator said its review ensures that differences between the generic products and the reference biologic do not affect the safety, efficacy, or quality of the drug. It added that the availability of generic drugs is expected to have a positive impact in Canada, including potential cost savings for patients and the healthcare system, and that many generic medicines in Canada are 45% to 90% cheaper than their brandname counterparts
This allows isolation of glucagon pathway contributions without the additional GIP variable present in Retatrutide
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