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A 250 mcg target amount equals 0.1 mL, or 10 insulin units
The commonly referenced therapeutic range of 0.25-0.5 mg daily (250-500 mcg) extrapolates from the effective rat dose of approximately 10 mcg/kg body weight
It also shifts melanin synthesis from dark pigment (eumelanin) to a lighter pigment (pheomelanin)
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