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Stay hydrated throughout the day to support metabolic functions

While this side effect may not be a dea-lbreaker for those taking the drug to aid their weight-loss journey, its not ideal

However, arginine level depletion in patients sustained for about a week and returned to baseline level, suggesting that resistance on ADI-PEG20 may arise upon prolonged drug treatment [140, 141]

Sci Rep (2017) 7:9100

9,10 Summary A large body of high-quality evidence suggests that in patients with obesity without diabetes, GLP-1 and GIP/GLP-1 receptor agonists are associated with significant regain of lost weight after therapy discontinuation