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5 for a graphical summary of the main results of the study), confirming their requirement for agonist-induced GLP-1R phosphorylation, and identifying the third serine doublet at position 451/452 as required for the recruitment of GRK2 to the stimulated receptor, as well as unveiling a previously unknown positive correlation between receptor phosphorylation and its capacity for cAMP generation downstream of GLP-1 stimulation in -cells

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Sun CH, Zheng W, Yang XH, Cai DB, Ng CH, Ungvari GS, et al

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