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For example, AZD8055 conjugated to albumin-stabilized gold nanoclusters (ABN-AZD) achieved tumor-selective drug release through glutathione-responsive linkers, 445 whereas albumin-bound rapamycin nanoparticles (nab-rapamycin, ABI-009) enhanced tumor accumulation and reduced systemic toxicity

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In addition, patients with a personal or family history of melanoma, numerous nevi, and/or atypical nevi should have total body skin examinations on a regular basis

There are other limits too

The study has been performed in accordance with the principles of Declaration of Helsinki