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Injectable forms generally offer stronger and more predictable results, while nasal sprays provide a simpler and more approachable option for patients prioritizing ease of use
According to the SURMOUNT-5 trial published in NEJM, tirzepatide produced 20.2% weight loss versus 13.7% for semaglutide
Losing muscle compromises metabolic health and elevates the risk of weight regain post-medication
ACS Omega 9:2852028533
One probable interpretation is that transport of molecules across the BBB is highly controlled and the ingestion of the abnormally high doses of drug may affect this
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