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They found that a stable GLP-1-estradiol conjugate caused greater weight loss in obese male mice than either GLP-1 controls or labile GLP-1-estradiol conjugates

They'll be much bigger and shaped differently than healthy ones

The state may become a hub for medical tourism

Clinical data show that within 24 weeks, over 75% improved mood and sleep, by 46 weeks about 70% had better memory and less brain fog, and over 70% of women found relief from menopause symptoms

Puopolo characterized this as evidence that the drugs reach the brain's reward circuitry, with the clearest data so far around alcohol and emerging signals for nicotine, opioids, and compulsive behaviors