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This next article in our series aims to provide an overview of incretins, examine the effects they exert on the body, and discuss their potential in the treatment of conditions associated with chronic inflammation

The most frequently reported adverse effects relate to the gastrointestinal system rather than direct cardiac effects, including nausea (occurring in approximately 15-20% of patients according to the SmPC), vomiting, diarrhoea, and constipation

Key nutrients to consider include: Protein: Reduced caloric intake during significant weight loss can lead to loss of lean muscle mass

A published study examining appetite and eating behaviors during retatrutide treatment in the phase 2 trial found that 31 of 36 retatrutide-treated participants (86%) reported changes in eating behaviors within the first eight weeks of treatment

Your provider may need to determine you aren't a suitable candidate for a brand-name GLP-1, for reasons such as an allergy to an ingredient in a brand-name med