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When GLP-1 activates these brain regions, two things happen: You feel full and satisfied, and naturally stop wanting to eat more High-calorie, high-sugar foods feel less appealing the craving for them is turned down A 2014 study used brain scans (fMRI) to show this happening in real time in human volunteers GLP-1 receptor activation actually reduced brain activity in the regions that process hunger and food rewards

(Basel) , 10 (6), 985 (2021)

Costa, L

These findings will be critical in determining whether retatrutide is approved for use in the UK [1] [2] [3] [4]

Similar results appear in studies on other connective tissues