However, a very small percentage of B12 from a supplemental dose is absorbed by passive diffusion, rather than by intrinsic factor, such that vegans can make up for taking B12 only once per day, or even only once per week, by taking larger doses than normally provided by food
It is a co-factor for methionine synthase, an enzyme involved in the methylation cycle, which is crucial for the metabolism of amino acids and the production of neurotransmitters
They are also necessary for the interconversion of amino acids such as the metabolism of histidine to glutamic acid and the interconversion of serine and glycine
It also improves skin tone and elasticity while reducing redness and irritation, which complements the regenerative effects of it
So, for a typical 1500mcg/ml strength, a single 1ml injection costs approximately AED 20-25