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miR-146a, for instance, has been shown to reduce neuroinflammation by promoting an anti-inflammatory phenotype in activated microglia, offering a novel therapeutic target to mitigate RGC damage (157)
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HA-344 and #231 as dual inhibitors of GPX4 and TXNRD1 in AML cells In the same line, we recently designed two covalent small molecule inhibitors, that can concomitantly inhibit GPX4 and TXDNR1, two critical proteins involved in the protection of cell from ferroptosis and apoptosis [39]
In integrative medicine, supplements play a significant role alongside conventional treatments, and it is important to consult healthcare professionals about their use and potential interactions
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