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A recent study has shown that the occurrence of IC/BPS in both monozygotic and dizygotic twins, regardless of gender, may not be solely due to genetic factors (Altman et al., 2011)
This can happen when you have a chronic disease that affects your pancreas, such as chronic pancreatitis or cystic fibrosis(an inherited disease in which thick mucus can damage organs)
MeCP2 mutations: progress towards understanding and treating Rett syndrome
Wenz T, Rossi SG, Rotundo RL, Spiegelman BM, Moraes CT
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