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However, the FDA has received voluntary reports from patients describing emotional numbness, reduced motivation, and depressive symptoms after starting GLP-1 therapy, though causality remains unclear

Spacing doses too close raises the risk of nausea, vomiting, and low blood sugar

But it's still unclear if there is a link between semaglutide use and milk production and/or the nutrient content of breast milk, so hopefully more research will determine any impacts on infant growth and development

Cost concerns or supply shortages

Protein, soluble and fermentable fiber, and healthy fats can all raise your own GLP-1 a little