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The most common side effects reported in trials include: Digestive issues Nausea (the most frequently reported side effect) Vomiting Diarrhoea Constipation Stomach pain or discomfort Loss of appetite Other reported effects Fatigue or tiredness Injection site reactions (redness, swelling, or irritation) Most side effects tend to be worse when starting the medication or increasing the dose, and often improve as your body adjusts

Mitochondria-targeted inhibitors of the human SIRT3 lysine deacetylase

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Hypoglycemia (Low Blood Sugar) While Zepbound is designed to lower high blood sugar, it rarely causes hypoglycemia on its own in people without type 2 diabetes

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