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In Phase 3 trials, the highest dose produced 28.7% average weight loss at 68 weeks nearly double what semaglutide achieves
The peptide also modulates inflammation by shifting macrophage polarization from the pro-inflammatory M1 phenotype to the reparative M2 phenotype , reducing levels of TNF-, IL-6, and IFN- PMID: 40789979
TNF-, tumor necrosis factor alpha
Ozempic face refers to the facial aesthetic change often seen in patients who experience rapid or significant weight loss while using GLP-1 medications
They are studied in different ways, so a better answer is not a clean one
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