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While tirzepatide is not primarily eliminated through the kidneys, the gastrointestinal effects of the medication, including potential nausea, vomiting, and diarrhea, could lead to dehydration and electrolyte imbalances that may be particularly problematic in patients with compromised kidney function
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Nausea affects 40-50 percent of users, with vomiting, diarrhea, constipation, and abdominal pain also common
Glutathione: The Occurrence and Quantitative Estimation of Glutathione in Tissues
Hypoxia and inflammation activate p53 via phosphorylation
