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Kircheis G (2016) Current state of knowledge of hepatic encephalopathy (Part V): clinical efficacy of l-ornithine-l-aspartate in the management of HE

Its anti-inflammatory properties have been observed in various contexts, improving nerve health and reducing chronic pain 4 5

2007;30:S4-S41

Some sites now advertise specific microdosing plans, with dosing determined by a telehealth clinician (albeit with no real clinical data backing up this approach)

Even though, considering the essentiality of copper in humans, the copper hypothesis of GHK mechanism of action seems very attractive, recent gene data may challenge this mechanism and demand more studies into GHKs mechanism of action