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Therefore, we acknowledge the absence of paired data from the two different assays as a limitation of this study
The TRIUMPH 4 trial reported the following rates at the 12mg dose level
e , Left, volcano plot showing relative fold change (log 2 ) in whole cell metabolite abundance versus log 10 (P value) from HEK293T cells expressing a sgRNA targeting intergenic region or sgRNA targeting SLC33A1
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