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Research done in diabetic rats shows magnesium supplements can boost GLP-1 release, regulate glucose metabolism, and improve insulin sensitivity

Pooled analyses from trials such as SUSTAIN-6 and LEADER reported reductions in albuminuria and slower declines in estimated glomerular filtration rates (eGFR), with pronounced benefits observed in those with lower baseline eGFR (41)

Gastroenterology 132 (6), 21312157

It would be another decade before these medications would be discovered, and two before the shot heard round the world would revolutionize the care for people with diabetes, excess fat (diagnosed with obesity), sleep apnea and more along with the diet and food industries, pharmaceutical care, dietary supplementation and fitness recommendations

Additionally, Zepbound may reduce the effectiveness of oral contraceptives, particularly during dose escalation